Demethylspheroidene O-methyltransferase
Demethylspheroidene O-methyltransferase (EC 2.1.1.210, 1-hydroxycarotenoid O-methylase, 1-hydroxycarotenoid methylase, 1-HO-carotenoid methylase, CrtF) is an enzyme with systematic name S-adenosyl-L-methionine:demethylspheroidene O-methyltransferase.[1][2][3] This enzyme catalyses the following chemical reaction
- S-adenosyl-L-methionine + demethylspheroidene S-adenosyl-L-homocysteine + spheroidene
| Demethylspheroidene O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.210 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
In Rhodopseudomonas capsulata and Rubrivivax gelatinosus the enzyme is involved in biosynthesis of spheroidene.
References
- Badenhop F, Steiger S, Sandmann M, Sandmann G (May 2003). "Expression and biochemical characterization of the 1-HO-carotenoid methylase CrtF from Rhodobacter capsulatus". FEMS Microbiology Letters. 222 (2): 237–42. doi:10.1016/s0378-1097(03)00302-1. PMID 12770713.
- Pinta V, Ouchane S, Picaud M, Takaichi S, Astier C, Reiss-Husson F (May 2003). "Characterization of unusual hydroxy- and ketocarotenoids in Rubrivivax gelatinosus: involvement of enzyme CrtF or CrtA". Archives of Microbiology. 179 (5): 354–62. doi:10.1007/s00203-003-0538-3. PMID 12664193. S2CID 30048505.
- Scolnik PA, Walker MA, Marrs BL (March 1980). "Biosynthesis of carotenoids derived from neurosporene in Rhodopseudomonas capsulata". The Journal of Biological Chemistry. 255 (6): 2427–32. doi:10.1016/S0021-9258(19)85909-4. PMID 7358679.
External links
- Demethylspheroidene+O-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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