David H. Adams

David H. Adams is an American cardiac surgeon and the Marie-Josée and Henry R. Kravis Professor and Chairman of the Department of Cardiothoracic Surgery, Icahn School of Medicine at Mount Sinai Hospital in New York City.[1][2] Dr. Adams is a recognized leader in the field of heart valve surgery and mitral valve reconstruction. As director of Mount Sinai Mitral Valve Repair Center, he has set national benchmarks with >99% degenerative mitral valve repair rates,[3] while running one of the largest valve repair programs in the United States. Dr. Adams is the co-inventor of 2 mitral valve annuloplasty repair rings – the Carpentier-McCarthy-Adams IMR ETlogix Ring and the Carpentier-Edwards Physio II Annuloplasty Ring,[4] and is a senior consultant with royalty agreements with Edwards Lifesciences. He is also the inventor of the Tri-Ad Adams Tricuspid Annuloplasty ring with a royalty agreement with Medtronic.[5] He is a co-author with Professor Alain Carpentier of the benchmark textbook in mitral valve surgery Carpentier's Reconstructive Valve Surgery.[6] He is also the National Co-Principal Investigator of the FDA pivotal trial of the Medtronic-CoreValve transcatheter aortic valve replacement device.[7]

David H. Adams
NationalityAmerican
OccupationCardiothoracic Surgeon
EmployerMount Sinai Hospital
TitleMarie-Josée and Henry R. Kravis Professor and Chairman

Biography

Adams is a cardiac surgeon at Mount Sinai Hospital in New York City, specializing in mitral valve repair. He is the author of over 800 publications (as of April 2020),[8] holds three patents (Patent number 7.959.673, 6.660.265 and 6.540.781) and is recognized as a leading surgeon scientist and medical expert, serving on the Editorial Boards of several medical journals, including the Annals of Thoracic Surgery and Cardiology.[9] Adams is a highly sought speaker both nationally and internationally, and has developed one of the world's largest video libraries of techniques in valve reconstruction.[10] He is co-director of the annual American College of Cardiology/American Association for Thoracic Surgery (AATS) Heart Valve Disease Summit,[11] and the Director of the biennial AATS Mitral Conclave.[12] He received his undergraduate and medical education at Duke University and completed his internship and residency in general and cardiothoracic surgery at Brigham and Women's Hospital and at Harvard Medical School. Adams followed that with a fellowship in the Cardiothoracic Unit at Harefield Hospital in London under Professor Sir Magdi Yacoub. In addition, he completed a two-year research fellowship under Professor Morris Karnovsky in the Department of Pathology at Harvard Medical School. He later served at Brigham and Women's Hospital as the Associate Chief of Cardiac Surgery and Director of the Brigham Primate Xeno-transplant Laboratory. He has been Chairman of the Department of Cardiothoracic Surgery at Mount Sinai Hospital since 2002.[13][14]

Scientific investigator

Adams' clinical interests include all aspects of heart valve surgery, with a special emphasis on mitral valve reconstruction.

Areas of research

Adams' major research interests include:[13]

  • Investigation of Ischemic Mitral Regurgitation
  • Outcomes Related to Mitral Valve Repair
  • Novel Mitral Valve Repair Strategies

Past research honors include the Alton Ochsner Research Scholarship from the American Association for Thoracic Surgery[15] and the Paul Dudley White Research Fellowship from the American Heart Association.[16] He has also received honorary Professorships from Capital University in Beijing and Keio University in Tokyo.[17]

Medical 'miracle'

In 2005 New York Magazine featured Adams as having performed "Medical Miracle #7" when, in 2004, he performed mitral valve surgery on actress Liana Pai, who was then six months pregnant with her first child.[18]

Immediate surgery was required to address Pai's aggressive bacterial infection. A conventional surgical procedure – arresting the heart during the operation, using a heart-and-lung machine, and following up with a regime of anti-clotting drugs – would have terminated the actress's pregnancy. With an incision across Pai's breast bone, Adams drained blood from her heart into a reservoir where it could be oxygenated before being returned to the aorta. In the meantime, he replaced two valves, both too badly damaged to attempt reconstruction with time limited by lack of a heart-and-lung machine, with compatible organic tissue – thereby eliminating the need for pregnancy-prohibiting anti-clotting drugs post-surgery.

"I was glad to be alive, of course, but until my baby was born, I wouldn't believe everything was okay... Ima came out perfect and healthy. She's healthy, headstrong, independent. Adams saved two lives at once."[18]

Awards and honors

Inventor
  • Carpentier A, Adams DH, Adzich, WV. Degenerative valvular disease specific annuloplasty ring sets, Patent filed with U.S. Patent and Trademark Office March 16, 2012[20]
  • Carpentier A, McCarthy P, Adams DH. Carpentier-McCarthy-Adams IMR ETlogix Annuloplasty Ring. Edwards Lifesciences Corporation, Irvine, CA 2004.[21]
  • Chen RH, Adams DH. Fresh, cryopreserved, or minimally fixed cardiac valvular xenografts. Patent filed with the U.S. Patent and Trademark Office October 16, 2000.[22][23]
  • Adams DH. Cryopreserved homografts having natural tissue sewing rings. Patent filed with the U.S. Patent and Trademark Office January 27, 1999.[24]

Peer-reviewed articles

Partial list:

References
  1. "Doctor Profile", Mount Sinai Hospital Archived August 1, 2019, at the Wayback Machine retrieved March 13, 2013
  2. "Points/Counterpoint: Should surgeons operate on functional tricuspid regurgitation?". www.mdedge.com. Archived from the original on November 17, 2019. Retrieved November 16, 2019.
  3. Castillo, J. G.; Anyanwu, A. C.; Fuster, V.; Adams, D. H. (2012). "A near 100% repair rate for mitral valve prolapse is achievable in a reference center: Implications for future guidelines". The Journal of Thoracic and Cardiovascular Surgery. 144 (2): 308–312. doi:10.1016/j.jtcvs.2011.12.054. PMID 22698565.
  4. Search. David H. Adams
  5. "Medtronic Tri-Ad Adams Tricuspid Annuloplasty Ring – First Implantation". Mitral Valce Reair Center. Archived from the original on November 16, 2019. Retrieved November 16, 2019.
  6. Carpentier's Reconstructive Valve Surger. Elsevier Health. 2010. ISBN 9780721691688.
  7. FDA Trial retrieved March 13, 2013
  8. "Adams DH – Search Results". PubMed. Retrieved April 25, 2020.
  9. "David H. Adams Assumes Presidency of the American Association for Thoracic Surgery". AATS. Archived from the original on November 16, 2019. Retrieved November 16, 2019.
  10. "David H Adams | Icahn School of Medicine". Icahn School of Medicine at Mount Sinai. Archived from the original on November 16, 2019. Retrieved November 16, 2019.
  11. "David H. Adams Assumes Presidency". www.aats.org. Archived from the original on November 16, 2019. Retrieved November 16, 2019.
  12. "2013 AATS Mitral Conclave". The Journal of Thoracic and Cardiovascular Surgery. 145 (3): 900–901. March 2013. doi:10.1016/s0022-5223(13)00103-7. ISSN 0022-5223.
  13. "David Adams | CTSNet". www.ctsnet.org. Retrieved November 16, 2019.
  14. "Mt. Sinai Pays Millions to Lure Top Harvard Surgeons | News | The Harvard Crimson". www.thecrimson.com. Archived from the original on June 4, 2015. Retrieved November 16, 2019.
  15. "The American Association for Thoracic Surgery". The Journal of Thoracic and Cardiovascular Surgery. 123 (3): 611–612. March 1, 2002. doi:10.1016/S0022-5223(02)70117-7. ISSN 0022-5223.
  16. Stevensville, Headquarters 198 Log Canoe Circle; States, MD 21666 United. "Cardiac surgery". Leaders in Pharmaceutical Business Intelligence (LPBI) Group. Archived from the original on November 16, 2019. Retrieved November 16, 2019.
  17. "David H. Adams, MD | Mitral Valve Repair Center". www.mitralvalverepair.org. Archived from the original on November 16, 2019. Retrieved November 16, 2019.
  18. Levine, Mark (June 5, 2005). "A Heart-Stopping Pregnancy". New York. Archived from the original on May 22, 2008. Retrieved July 24, 2009.
  19. "Doctor Profile", Mount Sinai Archived December 15, 2018, at the Wayback Machine retrieved March 13, 2013
  20. "Google Patents". patents.google.com. Retrieved November 16, 2019.
  21. "Edwards Introduces New Mitral Valve Repair Ring". www.edwards.com. Archived from the original on November 16, 2019. Retrieved November 16, 2019.
  22. WO 2001028604, "Fresh, cryopreserved, or minimally fixed cardiac valvular xenografts", issued 2000-10-16
  23. US 6660265, "Fresh, cryopreserved, or minimally cardiac valvular xenografts", issued 2000-10-16
  24. US 6540781, "Cryopreserved homografts and other stentless bioprosthetic heart valves having natural tissue sewing rings", issued 2000-12-14
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