D-lyxose ketol-isomerase
In enzymology, a D-lyxose ketol-isomerase (EC 5.3.1.15) is an enzyme that catalyzes the chemical reaction
- D-lyxose D-xylulose
| D-lyxose ketol-isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.3.1.15 | ||||||||
| CAS no. | 37318-42-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Hence, this enzyme has one substrate, D-lyxose, and one product, D-xylulose.
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is D-lyxose aldose-ketose-isomerase. Other names in common use include D-lyxose isomerase, and D-lyxose ketol-isomerase. This enzyme participates in pentose and glucuronate interconversions.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1QO2 and 1VZW.
References
- ANDERSON RL, ALLISON DP (1965). "Purification and Characterization of D-Lyxose Isomerase". J. Biol. Chem. 240: 2367–72. PMID 14304839.
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