D-lactate dehydratase
D-lactate dehydratase (EC 4.2.1.130, glyoxylase III) is an enzyme with systematic name (R)-lactate hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction
- (R)-lactate methylglyoxal + H2O
D-lactate dehydratase | |||||||||
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Identifiers | |||||||||
EC no. | 4.2.1.130 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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The enzyme converts methylglyoxal to (R)-lactate.
References
- Misra K, Banerjee AB, Ray S, Ray M (February 1995). "Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione". The Biochemical Journal. 305 (3): 999–1003. doi:10.1042/bj3050999. PMC 1136357. PMID 7848303.
- Subedi KP, Choi D, Kim I, Min B, Park C (August 2011). "Hsp31 of Escherichia coli K-12 is glyoxalase III". Molecular Microbiology. 81 (4): 926–36. doi:10.1111/j.1365-2958.2011.07736.x. PMID 21696459.
External links
- D-lactate+dehydratase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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