D-lactate dehydratase

D-lactate dehydratase (EC 4.2.1.130, glyoxylase III) is an enzyme with systematic name (R)-lactate hydro-lyase.[1][2] This enzyme catalyses the following chemical reaction

(R)-lactate methylglyoxal + H2O
D-lactate dehydratase
Identifiers
EC no.4.2.1.130
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme converts methylglyoxal to (R)-lactate.

References

  1. Misra K, Banerjee AB, Ray S, Ray M (February 1995). "Glyoxalase III from Escherichia coli: a single novel enzyme for the conversion of methylglyoxal into D-lactate without reduced glutathione". The Biochemical Journal. 305 (3): 999–1003. doi:10.1042/bj3050999. PMC 1136357. PMID 7848303.
  2. Subedi KP, Choi D, Kim I, Min B, Park C (August 2011). "Hsp31 of Escherichia coli K-12 is glyoxalase III". Molecular Microbiology. 81 (4): 926–36. doi:10.1111/j.1365-2958.2011.07736.x. PMID 21696459.


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