D-alanine gamma-glutamyltransferase

In enzymology, a D-alanine gamma-glutamyltransferase (EC 2.3.2.14) is an enzyme that catalyzes the chemical reaction

L-glutamine + D-alanine NH3 + gamma-L-glutamyl-D-alanine
D-alanine gamma-glutamyltransferase
Identifiers
EC no.2.3.2.14
CAS no.9046-27-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

Thus, the two substrates of this enzyme are L-glutamine and D-alanine, whereas its two products are NH3 and gamma-L-glutamyl-D-alanine.

This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is L-glutamine:D-alanine gamma-glutamyltransferase.

References

    • Kawasaki Y, Ogawa T, Sasaoka K (1982). "Occurrence and some properties of a novel gamma-glutamyltransferase responsible for the synthesis of gamma-L-glutamyl-D-alanine in pea-seedlings". Biochim. Biophys. Acta. 716: 194–200. doi:10.1016/0304-4165(82)90268-9.


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