D-4-hydroxyphenylglycine transaminase
In enzymology, a D-4-hydroxyphenylglycine transaminase (EC 2.6.1.72) is an enzyme that catalyzes the chemical reaction
- D-4-hydroxyphenylglycine + 2-oxoglutarate 4-hydroxyphenylglyoxylate + L-glutamate
| D-4-hydroxyphenylglycine transaminase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.6.1.72 | ||||||||
| CAS no. | 117444-05-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are D-4-hydroxyphenylglycine and 2-oxoglutarate, whereas its two products are 4-hydroxyphenylglyoxylate and L-glutamate.
This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is D-4-hydroxyphenylglycine:2-oxoglutarate aminotransferase. This enzyme is also called D-hydroxyphenylglycine aminotransferase. It employs one cofactor, pyridoxal phosphate.
References
- Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953.
- Probst C, Grotz M, Krettek C, Pape HC (2005). "Impact of hypothermia on the immunologic response after trauma and elective surgery". Surg. Technol. Int. 14: 41–50. PMID 16525953.
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