Coenzyme gamma-F420-2:alpha-L-glutamate ligase

Coenzyme gamma-F420-2:α-L-glutamate ligase (EC 6.3.2.32, MJ1001, CofF protein, gamma-F420-2:alpha-L-glutamate ligase) is an enzyme with systematic name L-glutamate:coenzyme gamma-F420-2 (ADP-forming).[1] This enzyme catalyses the following chemical reaction

ATP + coenzyme γ-F420-2 + L-glutamate ADP + phosphate + coenzyme α-F420-3
Coenzyme gamma-F420-2:α-L-glutamate ligase
Identifiers
EC no.6.3.2.32
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme caps the γ-glutamyl tail of the hydride carrier [[coenzyme F420]].

References

  1. Li H, Xu H, Graham DE, White RH (August 2003). "Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme F420 and tetrahydrosarcinapterin biosyntheses". Proceedings of the National Academy of Sciences of the United States of America. 100 (17): 9785–90. doi:10.1073/pnas.1733391100. PMC 187843. PMID 12909715.
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