Berefrine

Berefrine (INN, USAN), also known as burefrine, is a sympathomimetic and mydriatic agent that was never marketed.[1][2] It is an oxazolidine prodrug of phenylephrine, and hence, an α1-adrenergic receptor agonist.

Berefrine
Clinical data
ATC code
  • None
Identifiers
  • 3-[(5R)-3-Methyl-2-(2-methyl-2-propanyl)-1,3-oxazolidin-5-yl]phenol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC14H21NO2
Molar mass235.327 g·mol−1
3D model (JSmol)
  • CC(C)(C)C1N(C[C@H](O1)c2cccc(c2)O)C
  • InChI=1S/C14H21NO2/c1-14(2,3)13-15(4)9-12(17-13)10-6-5-7-11(16)8-10/h5-8,12-13,16H,9H2,1-4H3/t12-,13?/m0/s1
  • Key:ORIOFGXXYYXLNY-UEWDXFNNSA-N

References
  1. Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 615–. ISBN 978-0-412-46630-4.
  2. World Health Organization (2000). International Nonproprietary Names (INN) for Pharmaceutical Substances. World Health Organization. ISBN 978-0-11-986227-0.



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