Baccharis oxide synthase

Baccharis oxide synthase (EC 5.4.99.51) is an enzyme with systematic name (3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, baccharis-oxide-forming).[1] This enzyme catalyses the following chemical reaction

(3S)-2,3-epoxy-2,3-dihydrosqualene baccharis oxide
Baccharis oxide synthase
Identifiers
EC no.5.4.99.51
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme from Stevia rebaudiana also gives traces of other triterpenoids.

References

  1. Shibuya M, Sagara A, Saitoh A, Kushiro T, Ebizuka Y (November 2008). "Biosynthesis of baccharis oxide, a triterpene with a 3,10-oxide bridge in the A-ring". Organic Letters. 10 (21): 5071–4. doi:10.1021/ol802072y. PMID 18850716.
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