ASXL3

ASXL3
Identifiers
Aliases	ASXL3, BRPS, KIAA1713, additional sex combs like 3, transcriptional regulator, ASXL transcriptional regulator 3
External IDs	OMIM: 615115 MGI: 2685175 HomoloGene: 19371 GeneCards: ASXL3
Gene location (Human)
Chr.	Chromosome 18 (human)[1]
End	33,751,195 bp[1]
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)[2]
End	22,663,284 bp[2]
RNA expression pattern
	Top expressed in
	secondary oocyte; ; sperm; ; ganglionic eminence; ; Brodmann area 23; ; middle temporal gyrus; ; sural nerve; ; endothelial cell; ; superior frontal gyrus; ; entorhinal cortex; ; postcentral gyrus;
	Top expressed in
	superior cervical ganglion; ; hand; ; trigeminal ganglion; ; maxillary prominence; ; otolith organ; ; utricle; ; ganglionic eminence; ; vas deferens; ; abdominal wall; ; molar;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; DNA binding; chromatin binding; peroxisome proliferator activated receptor binding;
Cellular component	nucleus; PR-DUB complex;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; animal organ morphogenesis; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	80816
	211961
	ENSG00000141431
	ENSMUSG00000045215
	Q9C0F0
	Q8C4A5
	NM_030632
	NM_001167777
	NP_085135
	NP_001161249
	Wikidata
View/Edit Human	View/Edit Mouse

Putative Polycomb group protein ASXL3 is a protein that in humans is encoded by the ASXL3 gene.[5]

References

Fisher CL, Randazzo F, Humphries RK, Brock HW (March 2006). "Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family". Gene. 369: 109–18. doi:10.1016/j.gene.2005.10.033. PMID 16412590.
Katoh M, Katoh M (June 2004). "Identification and characterization of ASXL3 gene in silico". International Journal of Oncology. 24 (6): 1617–22. PMID 15138607.

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