ARHGDIG

Rho GDP-dissociation inhibitor 3 is a protein that in humans is encoded by the ARHGDIG gene.[5][6][7]

ARHGDIG
Identifiers
AliasesARHGDIG, RHOGDI-3, Rho GDP dissociation inhibitor gamma
External IDsOMIM: 602844 MGI: 108430 HomoloGene: 7337 GeneCards: ARHGDIG
Orthologs
SpeciesHumanMouse
Entrez

398

14570

Ensembl

ENSG00000242173

ENSMUSG00000073433

UniProt

Q99819

Q62160

RefSeq (mRNA)

NM_001176

NM_008113

RefSeq (protein)

NP_001167

NP_032139

Location (UCSC)Chr 16: 0.28 – 0.28 MbChr 17: 26.42 – 26.43 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

ARHGDIG has been shown to interact with RHOB.[8]

References

  1. GRCh38: Ensembl release 89: ENSG00000242173 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000073433 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Adra CN, Manor D, Ko JL, Zhu S, Horiuchi T, Van Aelst L, Cerione RA, Lim B (May 1997). "RhoGDIγ: A GDP-dissociation inhibitor for Rho proteins with preferential expression in brain and pancreas". Proc Natl Acad Sci U S A. 94 (9): 4279–84. Bibcode:1997PNAS...94.4279A. doi:10.1073/pnas.94.9.4279. PMC 20713. PMID 9113980.
  6. Brunet N, Morin A, Olofsson B (Apr 2002). "RhoGDI-3 regulates RhoG and targets this protein to the Golgi complex through its unique N-terminal domain". Traffic. 3 (5): 342–57. doi:10.1034/j.1600-0854.2002.30504.x. PMID 11967128. S2CID 19351109.
  7. "Entrez Gene: ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma".
  8. Zalcman G, Closson V, Camonis J, Honoré N, Rousseau-Merck MF, Tavitian A, Olofsson B (Nov 1996). "RhoGDI-3 is a new GDP dissociation inhibitor (GDI). Identification of a non-cytosolic GDI protein interacting with the small GTP-binding proteins RhoB and RhoG". J. Biol. Chem. 271 (48): 30366–74. doi:10.1074/jbc.271.48.30366. PMID 8939998.

Further reading


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