AKAP8L

A-kinase anchor protein 8-like is a protein that in humans is encoded by the AKAP8L gene.[5][6][7]

AKAP8L
Identifiers
AliasesAKAP8L, HA95, HAP95, NAKAP, NAKAP95, A-kinase anchoring protein 8 like
External IDsOMIM: 609475 MGI: 1860606 HomoloGene: 8658 GeneCards: AKAP8L
Orthologs
SpeciesHumanMouse
Entrez

26993

54194

Ensembl

ENSG00000011243

ENSMUSG00000002625

UniProt

Q9ULX6

Q9R0L7

RefSeq (mRNA)

NM_001291478
NM_014371

NM_017476

RefSeq (protein)

NP_001278407
NP_055186

n/a

Location (UCSC)Chr 19: 15.38 – 15.42 MbChr 17: 32.32 – 32.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

AKAP8L has been shown to interact with:

References

  1. GRCh38: Ensembl release 89: ENSG00000011243 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000002625 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Westberg C, Yang JP, Tang H, Reddy TR, Wong-Staal F (Jul 2000). "A novel shuttle protein binds to RNA helicase A and activates the retroviral constitutive transport element". The Journal of Biological Chemistry. 275 (28): 21396–21401. doi:10.1074/jbc.M909887199. PMID 10748171.
  6. Orstavik S, Eide T, Collas P, Han IO, Taskén K, Kieff E, Jahnsen T, Skålhegg BS (Jan 2000). "Identification, cloning and characterization of a novel nuclear protein, HA95, homologous to A-kinase anchoring protein 95". Biology of the Cell. 92 (1): 27–37. doi:10.1016/S0248-4900(00)88761-4. PMID 10761695. S2CID 1354592.
  7. "Entrez Gene: AKAP8L A kinase (PRKA) anchor protein 8-like".
  8. Yang JP, Tang H, Reddy TR, Wong-Staal F (Aug 2001). "Mapping the functional domains of HAP95, a protein that binds RNA helicase A and activates the constitutive transport element of type D retroviruses". The Journal of Biological Chemistry. 276 (33): 30694–700. doi:10.1074/jbc.M102809200. PMID 11402034.
  9. Martins SB, Eide T, Steen RL, Jahnsen T, Skålhegg BS, Collas P (Nov 2000). "HA95 is a protein of the chromatin and nuclear matrix regulating nuclear envelope dynamics". Journal of Cell Science. 113 Pt 21 (21): 3703–13. doi:10.1242/jcs.113.21.3703. PMID 11034899.
  10. Martins S, Eikvar S, Furukawa K, Collas P (Jan 2003). "HA95 and LAP2 beta mediate a novel chromatin-nuclear envelope interaction implicated in initiation of DNA replication". The Journal of Cell Biology. 160 (2): 177–88. doi:10.1083/jcb.200210026. PMC 2172640. PMID 12538639.

Further reading


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