ABCA10

ATP binding cassette subfamily A member 10 is a protein that in humans is encoded by the ABCA10 gene. [3]

ABCA10
Identifiers
AliasesABCA10, EST698739, ATP binding cassette subfamily A member 10
External IDsOMIM: 612508 HomoloGene: 122432 GeneCards: ABCA10
Orthologs
SpeciesHumanMouse
Entrez

10349

n/a

Ensembl

ENSG00000154263

n/a

UniProt

Q8WWZ4

n/a

RefSeq (mRNA)

NM_080282
NM_001377321

n/a

RefSeq (protein)

NP_525021
NP_001364250

n/a

Location (UCSC)Chr 17: 69.15 – 69.24 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Function

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This gene is clustered among 4 other ABC1 family members on 17q24, but neither the substrate nor the function of this gene is known. [provided by RefSeq, Jul 2008].

References

  1. GRCh38: Ensembl release 89: ENSG00000154263 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Entrez Gene: ATP binding cassette subfamily A member 10". Retrieved 2018-07-27.

Further reading

  • Wenzel JJ, Kaminski WE, Piehler A, Heimerl S, Langmann T, Schmitz G (July 2003). "ABCA10, a novel cholesterol-regulated ABCA6-like ABC transporter". Biochem. Biophys. Res. Commun. 306 (4): 1089–98. doi:10.1016/s0006-291x(03)01097-0. PMID 12821155.


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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