Dyspropterin

Dyspropterin (6-pyruvoyltetrahydropterin, 6-PTHB) is an intermediate in tetrahydrobiopterin biosynthesis. It is the product of the enzyme 6-pyruvoyltetrahydropterin synthase and the substrate of two enzymes, 6-pyruvoyltetrahydropterin 2'-reductase and sepiapterin reductase.

Dyspropterin
Names
Preferred IUPAC name
1-(2-Amino-4-oxo-5,6,7,8-tetrahydro-1H-pteridin-6-yl)propane-1,2-dione
Systematic IUPAC name
1-(2-Amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)propane-1,2-dione
Other names
6-Pyruvoyltetrahydropterin; 6-PTHB
Identifiers
3D model (JSmol)
3DMet
Abbreviations 6-PTHB
ChEBI
ChemSpider
KEGG
MeSH Dyspropterin
UNII
  • InChI=1S/C9H11N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h4,12H,2H2,1H3,(H4,10,11,13,14,17)
    Key: WBJZXBUVECZHCE-UHFFFAOYSA-N
  • CC(=O)C(=O)C1CNC2=C(N1)C(=O)N=C(N)N2
Properties
C9H11N5O3
Molar mass 237.219 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Dyspropterin exists in all living organisms, ranging from bacteria to humans.[1] Dyspropterin has been detected, but not quantified in, a few different foods, such as anatidaes (Anatidae), chickens (Gallus gallus), and domestic pigs (Sus scrofa domestica).[2] This could make dyspropterin a potential biomarker for the consumption of these foods.[3]

See also

References
  1. "Showing Compound Dyspropterin (FDB022481) - FooDB". foodb.ca. Retrieved 2022-03-30.
  2. "Showing Compound Dyspropterin (FDB022481) - FooDB". foodb.ca. Retrieved 2022-03-30.
  3. "Showing Compound Dyspropterin (FDB022481) - FooDB". foodb.ca. Retrieved 2022-03-30.


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