2-dehydro-3-deoxy-L-pentonate aldolase
The enzyme 2-dehydro-3-deoxy-L-pentonate aldolase (EC 4.1.2.18) catalyzes the chemical reaction
- 2-dehydro-3-deoxy-L-pentonate pyruvate + glycolaldehyde
2-dehydro-3-deoxy-L-pentonate aldolase | |||||||||
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Identifiers | |||||||||
EC no. | 4.1.2.18 | ||||||||
CAS no. | 9076-49-7 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase (pyruvate-forming). Other names in common use include 2-keto-3-deoxy-L-pentonate aldolase, 2-keto-3-deoxy-L-arabonate aldolase, 2-keto-3-deoxy-D-xylonate aldolase, 3-deoxy-D-pentulosonic acid aldolase, and 2-dehydro-3-deoxy-L-pentonate glycolaldehyde-lyase. This enzyme participates in fructose and mannose metabolism.
References
- Dahms AS, Anderson RL (1969). "2-keto-3-deoxyl-L-arabonate aldolase and its role in a new pathway of L-arabinose degradation". Biochem. Biophys. Res. Commun. 36 (5): 809–14. doi:10.1016/0006-291X(69)90681-0. PMID 5808295.
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