2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase
2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase (EC 5.3.3.18, paaG (gene), 1,2-epoxyphenylacetyl-CoA isomerase) is an enzyme with systematic name 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase.[1][2] This enzyme catalyses the following chemical reaction
- 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA 2-oxepin-2(3H)-ylideneacetyl-CoA
| 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.3.3.18 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme catalyses the reversible isomerization of 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA.
References
- Ismail W, El-Said Mohamed M, Wanner BL, Datsenko KA, Eisenreich W, Rohdich F, Bacher A, Fuchs G (July 2003). "Functional genomics by NMR spectroscopy. Phenylacetate catabolism in Escherichia coli". European Journal of Biochemistry. 270 (14): 3047–54. doi:10.1046/j.1432-1033.2003.03683.x. PMID 12846838.
- Teufel R, Mascaraque V, Ismail W, Voss M, Perera J, Eisenreich W, Haehnel W, Fuchs G (August 2010). "Bacterial phenylalanine and phenylacetate catabolic pathway revealed". Proceedings of the National Academy of Sciences of the United States of America. 107 (32): 14390–5. Bibcode:2010PNAS..10714390T. doi:10.1073/pnas.1005399107. PMC 2922514. PMID 20660314.
External links
- 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA+isomerase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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