1L-myo-inositol 1-phosphate cytidylyltransferase

1L-myo-inositol 1-phosphate cytidylyltransferase (EC 2.7.7.74, CTP:inositol-1-phosphate cytidylyltransferase (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)), IPCT (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)), L-myo-inositol-1-phosphate cytidylyltransferase) is an enzyme with systematic name CTP:1L-myo-inositol 1-phosphate cytidylyltransferase.[1] This enzyme catalyses the following chemical reaction

CTP + 1L-myo-inositol 1-phosphate diphosphate + CDP-1L-myo-inositol
1L-myo-inositol 1-phosphate cytidylyltransferase
Identifiers
EC no.2.7.7.74
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

This enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate.

References

  1. Rodrigues MV, Borges N, Henriques M, Lamosa P, Ventura R, Fernandes C, Empadinhas N, Maycock C, da Costa MS, Santos H (August 2007). "Bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase, the key enzyme for di-myo-inositol-phosphate synthesis in several (hyper)thermophiles". Journal of Bacteriology. 189 (15): 5405–12. doi:10.1128/JB.00465-07. PMC 1951816. PMID 17526717.
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