(-)-alpha-cuprenene synthase

(–)-α-Cuprenene synthase (EC 4.2.3.95, Cop6) is an enzyme with systematic name (–)-α -cuprenene hydrolase (cyclizing, (–)-α-cuprenene-forming).[1] This enzyme catalyses the following chemical reaction

(2E,6E)-farnesyl diphosphate (–)-α-cuprenene + diphosphate
(–)-α-cuprenene synthase
Identifiers
EC no.4.2.3.95
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Search
PMCarticles
PubMedarticles
NCBIproteins

The enzyme from the fungus Coprinopsis cinerea produces (–)-α-cuprenene with high selectivity.

References

  1. Lopez-Gallego F, Agger SA, Abate-Pella D, Distefano MD, Schmidt-Dannert C (May 2010). "Sesquiterpene synthases Cop4 and Cop6 from Coprinus cinereus: catalytic promiscuity and cyclization of farnesyl pyrophosphate geometric isomers". ChemBioChem. 11 (8): 1093–106. doi:10.1002/cbic.200900671. PMC 2873112. PMID 20419721.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.