(+)-alpha-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing)
(+)-α-Santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) (EC 4.2.3.50, SBS) is an enzyme with systematic name (2Z,6Z)-farnesyl diphosphate lyase (cyclizing; (+)-α-santalene-forming).[1] This enzyme catalyses the following chemical reaction
- (2Z,6Z)-farnesyl diphosphate (+)-α-santalene + diphosphate
| (+)-α-santalene synthase ((2Z,6Z)-farnesyl diphosphate cyclizing) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.50 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme synthesizes a mixture of sesquiterpenoids from (2Z,6Z)-farnesyl diphosphate.
References
- Sallaud C, Rontein D, Onillon S, Jabès F, Duffé P, Giacalone C, Thoraval S, Escoffier C, Herbette G, Leonhardt N, Causse M, Tissier A (January 2009). "A novel pathway for sesquiterpene biosynthesis from Z,Z-farnesyl pyrophosphate in the wild tomato Solanum habrochaites". The Plant Cell. 21 (1): 301–17. doi:10.1105/tpc.107.057885. PMC 2648096. PMID 19155349.
External links
- (+)-alpha-santalene+synthase+((2Z,6Z)-farnesyl+diphosphate+cyclizing) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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