(+)-Caryolan-1-ol synthase
(+)-Caryolan-1-ol synthase (EC 4.2.1.138, GcoA) is an enzyme with systematic name (+)-β-caryophyllene hydrolase (cyclizing, (+)-caryolan-1-ol-forming).[1] This enzyme catalyses the following chemical reaction
- (+)-β-caryophyllene + H2O (+)-caryolan-1-ol
| (+)-Caryolan-1-ol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.1.138 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme also forms (+)-β-caryophyllene from farnesyl diphosphate (EC 4.2.3.89).
References
- Nakano C, Horinouchi S, Ohnishi Y (August 2011). "Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus". The Journal of Biological Chemistry. 286 (32): 27980–7. doi:10.1074/jbc.m111.265652. PMC 3151043. PMID 21693706.
External links
- (+)-caryolan-1-ol+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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