Introduction

SPM has extensive developer documentation in the headers of the source files. To view the documentation of a function either open the corresponding source file or call help function from the MATLAB command line. Make sure that the SPM folder is in MATLABs search path.

Reading image headers and data

• spm_vol – header information
• spm_read_vols – for reading entire volumes (see also: spm_vol)
• spm_slice_vol – for arbitrary planes
• spm_sample_vol – any voxels
• spm_get_data (spm_sample_vol) – any voxels from multiple volumes
• spm_bsplins (spm_bsplinc) – NB spm_slice_vol and spm_sample_vol offer polynomial or sinc interpolation; these functions provide b-spline interp as used in spm_reslice

Writing data

• spm_write_vol (spm_vol)
• spm_create_vol
• spm_write_plane

Reading and writing data with the alternative NIfTI class library

• nifti (@nifti/Contents, @nifti/create)
• file_array (@file_array/Contents)

Geometry, voxel-world mappings

• spm_get_space – get the voxel-world mapping matrix (a rigid or affine transform, in homogeneous coordinates)
• spm_imatrix – convert above matrix to parametrised form
• spm_matrix – convert parameter vector to affine matrix
• spm_check_orientations

Linear (rigid/affine) registration and reslicing

• spm_realign
• spm_coreg (spm_reslice)
• spm_affreg
• spm_reslice – needs reference image; see following for reslicing to specified geometry
• reorient (resize_img) – available from John's Gems 2 and 3

Preprocessing, including segmentation and non-linear normalisation

• spm_preproc (spm_config_preproc, spm_prep2sn, spm_preproc_write) – SPM5's unified segmentation and normalisation
• spm_normalise – the old pre-SPM5 non-unified spatial normalisation
• spm_segment – the old pre-SPM5 non-unified tissue segmentation
• spm_smooth

Processing

• spm_imcalc – perform arbitrary calculations on volumes (low level function)
• spm_imcalc_ui – high level convenience wrapper for spm_imcalc

Statistics

• spm_ancova (spm_reml_ancova) – unused by SPM itself, but often useful for scripting or educational purposes

Viewing data

• spm_check_registration (spm_image, spm_orthviews) – the ubiquitous three orthogonal views
• slover – slices through images, overlays of thresholded or raw statistics; see also slice_overlay
• spm_mip_ui (spm_mip) – maximum intensity projections or glass brain images

Configuration

• spm_defaults
• spm_get_defaults

Batch System

• spm_select
• spm_jobman

Reading and writing a volume (to replace NaNs with zeros)

A simpler (but more memory-hungry) version of an old Gem. See the SPM8 version of gem for an example of plane-wise reading and writing.

fnm = spm_select(1, 'image');
[pth, bnm, ext] = spm_fileparts(fnm);
VI = spm_vol(fnm);
VO = VI; % copy input info for output image
VO.fname = fullfile(pth, [bnm '_zn' ext]);
img = spm_read_vols(VI);
img(isnan(img)) = 0; % use ~isfinite instead of isnan to replace +/-inf with zero
spm_write_vol(VO,img);